November 12, 2026: Think Tank on Advancing Precision Medicine in Rare Cancers Learn more and register.×
Think Tank on Advancing Precision Medicine in Rare Cancers logo

The Think Tank on Advancing Precision Medicine in Rare Cancers is a highly interactive one-day meeting that brings together clinicians, researchers, industry representatives, advocates, and patients to collaborate on common challenges in rare cancer research and treatment.

Leveraging the successful Think Tank model established through over a decade of TargetCancer Foundation meetings, it creates a collaborative environment where diverse perspectives and ideas thrive. This meeting also builds on the progress made through TargetCancer Foundation’s TCF-001 TRACK study, a nationwide, decentralized, patient-driven clinical trial studying precision medicine in rare cancers.

The 5th Annual Think Tank on Advancing Precision Medicine in Rare Cancers will take place at The State Room in Boston, MA on Thursday, November 12, 2026.

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Please note: to preserve the collaborative nature of this scientific meeting, this is an in-person only meeting with no virtual option. If you have any questions, please contact us at [email protected].

Eileen OReilly Headshot from

2026 Scientific Keynote

We are honored to welcome Dr. Eileen O’Reilly of Memorial Sloan Kettering Cancer Center as our Scientific Keynote Speaker at the 5th Annual Think Tank on Advancing Precision Medicine in Rare Cancers.

Dr. O’Reilly will present on: “The RAS Paradigm Shift in the Treatment of Pancreas Cancer and RAS-Driven Rare Cancers”.

Join us in Boston to learn how these novel targeted strategies are advancing clinical care and reshaping treatment options for patients with rare cancers.

Meeting Details

Agenda

*Additional speakers will be added as they are confirmed – agenda is subject to change.

7:30 AM NETWORKING BREAKFAST
8:00 AM WELCOME
  Jim Palma, TargetCancer Foundation
8:30 AM PATIENT KEYNOTE
  The Life Inside the Science: A Patient’s Perspective on Rare Cancer
  Matt Paradise, Patient Advocate
8:50 AM SESSION 1: REWRITING RARE CANCER OUTCOMES
  Tumor Agnostic Biomarkers in Rare Cancers: Influence of Therapy on Outcome
  PRESENTER AND MODERATOR: Razelle Kurzrock, MD, Medical College of Wisconsin
  Ezra Cohen, MD, Tempus
  Corrie Painter, PhD, Even One Ventures
9:50 AM SESSION 2: AGNOSTIC BY DESIGN
  Five Years That Redrew the Map of Rare Cancer Precision Oncology – and the Next Frontier
  Vivek Subbiah, MD, Stanford University School of Medicine
10:20 AM MORNING BREAK
10:40 AM SESSION 3: RISING INCIDENCE AND TREATMENT IMPLICATIONS FOR RARE CANCERS IN YOUNG POPULATIONS
  Ag(e)nostic Precision Oncology: An Expectation, Not an Exception
  Matthew Kudek, MD, Medical College of Wisconsin
  Talk Title: To be announced
  Haley Ellis, MD, Mass General Brigham
11:50 AM EVAN SCHUMACHER FUND FOR RARE CANCER RESEARCH EARLY INVESTIGATOR AWARD ABSTRACT PRESENTATION
12:15 PM NETWORKING LUNCH
1:00 PM SCIENTIFIC KEYNOTE:
  The RAS Paradigm Shift in the Treatment of Pancreas Cancer and RAS-Driven Rare Cancers
  Eileen O’Reilly, MD, Memorial Sloan Kettering Cancer Center
1:30 PM CASE STUDY PRESENTATION: TCF-001 TRACK MOLECULAR TUMOR BOARD
  MODERATOR: Razelle Kurzrock, MD, Medical College of Wisconsin, TRACK Principal Investigator
  Shumei Kato, MD, University of California San Diego, TRACK Co-Principal Investigator
  Mina Nikanjam, MD, PhD, University of California San Diego, TRACK Co-Principal Investigator
  Vivek Subbiah, MD, Stanford University School of Medicine, TRACK Co-Principal Investigator
  Bita Esmaeli, MD, MA, FACS, Mann Eye Institute; TRACK MTB Member
  Bicky Thapa, MD, MS, FACP, Dana-Farber Cancer Institute, TRACK MTB Member
  Hetal Vig, MS, MGC, TargetCancer Foundation
2:30 PM NETWORKING BREAK
2:45 PM SESSION 4: EMERGING DIAGNOSTICS IN RARE CANCERS
  Advancing Rare Cancer Research Through Innovative Biomarker Development
  Simon Heeke, PhD, AstraZeneca
  Speaker 2: To be announced
4:00 PM SESSION 5: UNKNOWN PRIMARY, UNMET NEED: THE FUTURE OF CUP TREATMENT
  MODERATOR: Vivek Subbiah, MD, Stanford University School of Medicine
  Shumei Kato, MD, University of California San Diego
  Kanwal Raghav, MBBS, MD, UT MD Anderson Cancer Center
4:45 PM CLOSING ADVOCACY DISCUSSION
5:15 PM COCKTAIL RECEPTION AND POSTER PRESENTATIONS

Venue

The State Room, located at 60 State Street, is centrally located in downtown Boston, MA.

Accommodations

A room block has been reserved at Canopy by Hilton Boston Downtown, located a five-minute walk (0.3 miles) from the meeting venue. Meeting attendees will receive a discounted room rate of $299/night + tax.

Please click here to reserve a room before the discount ends on Monday, October 12, 2026.

Call for Submissions: Early Career Investigator Abstracts

The Evan Schumacher Fund for Rare Cancer Research Early Investigator Award

Encouraging Early Career Investigators to Make a Difference in Rare Cancers

The Evan Schumacher Fund for Rare Cancer Research Early Investigator Award honors the life of Evan Schumacher by supporting early career investigators who are focused on studying rare cancers. We are pleased to invite early investigators (within 5 years of fellowship or terminal degree) from universities, medical, and scientific institutions to submit an abstract, and the top three abstracts will receive a cash award along with the opportunity to present their research in front of rare cancer and precision medicine experts at the 2026 Think Tank on Advancing Precision Medicine in Rare Cancers.

  • 1st: $4,000 award, plus an opportunity to present the abstract live at the Think Tank and also present the related poster at the evening reception.
  • 2nd: $2,000 award, plus an opportunity to present the related poster at the evening reception.
  • 3rd: $1,000 award, plus an opportunity to present the related poster at the evening reception.

The deadline to submit your abstract is Monday, September 14, 2026.

Scientific meeting

2026 Steering Committee

John Iafrate, MD, PhD

A. John Iafrate, MD, PhD

Massachusetts General Hospital

Harvard Medical School

Razelle Kurzrock, MD

Razelle Kurzrock, MD

Froedtert and Medical College

of Wisconsin

2026 Meeting Sponsors

AstraZeneca Logo Colour 2025
FMI Logo Slate 300ppi 2025
JazzPharma Logo FullColor 2025
Lilly Logo RGB Red 2025
Servier Logo Color 2025
Taiho Oncology Logo Horizontal 2025

What participants are saying

This was a fantastic #RareCancer #PrecisionMedicine meeting @targetcancer in Boston! So much enthusiasm from patients and patient advocates to move the field forward.
Vivek Subbiah MD
Vivek Subbiah, MD
Sarah Cannon Research Institute
Originally posted on Twitter
This is genuinely the best rare cancer meeting I have ever attended.
Vivek Subbiah MD

Razelle Kurzrock, MD
Froedtert and Medical College of Wisconsin

…thank you for allowing me to be a part of the discussion of challenges, goals, opportunities and best practices in addressing the needs of patients facing rare cancers. What a wonderful group of humans you gathered. I was so inspired.
Vivek Subbiah MD
Katie Ortman Doble
Patient Keynote Speaker,
2023 Think Tank on Advancing Precision Medicine in Rare Cancers

View and download materials from past meetings

TargetCancer Icon, White

TCF-001 TRACK Molecular Tumor Board 2025:
Prostatic Urethral Cancer

Presented at the TargetCancer Foundation Think Tank on Advancing Precision Medicine in Rare Cancers, October 29, 2025, Boston MA

We are grateful to our industry partners for supporting these meetings and for their dedication to developing treatments for patients with rare cancers.